2(3H)-Furanone, 3-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]dihydro-, (E)- (9CI) - Names and Identifiers
2(3H)-Furanone, 3-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]dihydro-, (E)- (9CI) - Physico-chemical Properties
Molecular Formula | C19H26O3
|
Molar Mass | 302.41 |
Density | 1.096±0.06 g/cm3(Predicted) |
Boling Point | 429.1±45.0 °C(Predicted) |
pKa | 11.51±0.50(Predicted) |
Storage Condition | 2-8°C,避光,干燥,密封 |
In vitro study | The synthesized α-benzulidene-γ-butyrolactones are pure isomers (either cis or trans ). PGS-IN-1 is the trans isomer. PGS-IN-1 exhibits potent antiinflammatrory and PGS inhibitory activity (IC 50 =0.28 μM). PGS-IN-1 also shows potent inhibitory activity against 5-lipoxygenase (IC 50 =1.05 μM). |
2(3H)-Furanone, 3-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]dihydro-, (E)- (9CI) - Introduction
PGS-IN-1 is a chemical called Protagonist-IN-1. It is a small molecule compound with a variety of properties and uses.
The main property of PGS-IN-1 is its multi-target inhibitory activity. It can modulate cellular function by targeting multiple cell signaling pathways. In particular, PGS-IN-1 is capable of inhibiting multiple protein kinases, such as SRC, BRK, Lck and YES. Due to its multi-target characteristics, PGS-IN-1 has a wide range of potential applications in biomedical research.
PGS-IN-1 are mainly used to study cell signaling pathways and oncology. It can be used as a component of extracellular matrix to study cell behavior and growth regulation. In addition, PGS-IN-1 can also be used to gain insight into the signaling pathways of cancer cells and provide new targets for the development of anti-cancer drugs.
Regarding the method of preparing PGS-IN-1, the specific synthetic route may vary depending on the researcher and laboratory. In general, the preparation of PGS-IN-1 requires the techniques and equipment of synthetic organic chemistry, involving multi-step reactions.
when using the PGS-IN-1 should comply with the relevant safety procedures. Since it is a laboratory chemical that may be potentially toxic to humans, appropriate safety measures need to be taken. This includes wearing protective gloves, safety glasses and laboratory coats to avoid contact with skin and inhalation of gases. In addition, attention should be paid to the correct storage and handling of PGS-IN-1, and avoid mixing with other chemical substances to avoid potential hazards. Before using the PGS-IN-1, make sure to read and understand the relevant safety data sheets carefully.
Last Update:2024-04-09 21:04:16